NVS-BPTF-1

• CAT Number: I047651
• CAS Number: 2662454-54-6
• Molecular Formula: C26H28FN7O3S
• Molecular Weight: 537.61
• Purity: ≥95%
• IUPAC Name: 7-(1-cyclopropylpyrazol-4-yl)-2-[2-fluoro-4-(4-methylpiperazin-1-yl)sulfonylanilino]-3-methylpyrido[1,2-a]pyrimidin-4-one
• InChI: InChI=1S/C26H28FN7O3S/c1-17-25(29-23-7-6-21(13-22(23)27)38(36,37)32-11-9-31(2)10-12-32)30-24-8-3-18(15-33(24)26(17)35)19-14-28-34(16-19)20-4-5-20/h3,6-8,13-16,20,29H,4-5,9-12H2,1-2H3
• SMILES: CC1=C(N=C2C=CC(=CN2C1=O)C3=CN(N=C3)C4CC4)NC5=C(C=C(C=C5)S(=O)(=O)N6CCN(CC6)C)F

NVS-BPTF-1 is a potent, selective and cell active chemical probe for BPTF (IC50 value of 56 nM and Kd value of 71 nM).
KEYWORDS: NVS-BPTF-1 | supplier | BPTF probe | NVS-BPTF1 | NVS-BPTF 1 | CAS [2662454-54-6] | Histone | BRPF1 (BRD) | Probe | Proteins | FALZ | Bromodomain PHD Finger Transcription Factor | Melanoma

Reference

NVS-BPTF-1 A chemical probe for BPTF. Structural Genomics Consortium (SGC).