NVX-108

• CAT Number: I033733
• CAS Number: 678-26-2
• Molecular Formula: C5F12
• Molecular Weight: 288.04
• Purity: 98%
• Synonyms: Perfluoropentane; Dodecafluoropentane; DDFP; NVX108; NVX 108; NVX-108
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: Perfluoropentane; Dodecafluoropentane
• InChI: InChI=1S/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17
• InChIKey: NJCBUSHGCBERSK-UHFFFAOYSA-N
• SMILES: FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

NVX-108 (Cat.No:I033733) is an exceptional oxygen transporter which increases brain tissue oxygen tension (PbtO2) when administered soon after traumatic brain injury (TBI).

Reference

1: Mullah SH, Saha BK, Abutarboush R, Walker PB, Haque A, Arnaud FG, Hazzard B, Auker CR, McCarron RM, Scultetus AH, Moon-Massat P. Perfluorocarbon NVX-108 increased cerebral oxygen tension after traumatic brain injury in rats. Brain Res. 2016 Mar 1;1634:132-139. doi: 10.1016/j.brainres.2016.01.012. Epub 2016 Jan 12. PubMed PMID: 26794250.
2: Moon-Massat PF, Abutarboush R, Pappas G, Haque A, Aligbe C, Arnaud F, Auker C, McCarron R, Scultetus A. Effects of perfluorocarbon dodecafluoropentane (NVX-108) on cerebral microvasculature in the healthy rat. Curr Drug Discov Technol. 2014;11(3):220-6. PubMed PMID: 25007887.