NXY-059

• CAT Number: I002196
• CAS Number: 168021-79-2
• Molecular Formula: C11H13NO7S2 • 2Na
• Molecular Weight: 381.30
• Purity: ≥95%
• Synonyms: Disufenton Sodium;Cerovive;CPI-22
• Target: NF-κB
• Solubility: DMSO ≥74mg/mL Water ≥74mg/mL Ethanol ≥1.6mg/mL
• Storage: 3 years -20C powder
• IUPAC Name: disodium;4-[(Z)-[tert-butyl(oxido)azaniumylidene]methyl]benzene-1,3-disulfonate
• InChI: InChI=1S/C11H15NO7S2.2Na/c1-11(2,3)12(13)7-8-4-5-9(20(14,15)16)6-10(8)21(17,18)19;;/h4-7H,1-3H3,(H,14,15,16)(H,17,18,19);;/q;2*+1/p-2/b12-7-
• InChIKey: XLZOVRYBVCMCGL-BPNVQINPSA-L
• SMILES: CC(C)(C)/[N+](=C/C1=C(C=C(C=C1)S(=O)(=O)[O-])S(=O)(=O)[O-])/[O-].[Na+].[Na+]

NXY-059（Cat No.:I002196）is a neuroprotective agent developed for the treatment of acute ischemic stroke and other neurodegenerative conditions. It functions as a free radical scavenger, targeting reactive oxygen species (ROS) and peroxynitrite, which contribute to neuronal damage following ischemic injury. By inhibiting oxidative stress and preserving cellular integrity, NXY-059 has shown promise in reducing brain tissue damage and improving functional recovery in preclinical and early clinical trials. Although its efficacy in stroke management appeared promising, further research and clinical studies are required to confirm its safety, effectiveness, and long-term benefits in neuroprotection.