For research use only. Not for therapeutic Use.
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation[1].
NY2267 strongly inhibits oncogenic transformation induced by Myc[1].
| Catalog Number | I044524 |
| CAS Number | 886053-73-2 |
| Synonyms | tert-butyl 2-[6-[2-(cyclohexylamino)-1-[(4-methoxyphenyl)methyl-(pyridine-2-carbonyl)amino]-2-oxoethyl]naphthalen-2-yl]oxyacetate |
| Molecular Formula | C38H43N3O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C38H43N3O6/c1-38(2,3)47-34(42)25-46-32-20-17-27-22-29(16-15-28(27)23-32)35(36(43)40-30-10-6-5-7-11-30)41(37(44)33-12-8-9-21-39-33)24-26-13-18-31(45-4)19-14-26/h8-9,12-23,30,35H,5-7,10-11,24-25H2,1-4H3,(H,40,43) |
| InChIKey | RVGDACCXDZIPOB-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)COC1=CC2=C(C=C1)C=C(C=C2)C(C(=O)NC3CCCCC3)N(CC4=CC=C(C=C4)OC)C(=O)C5=CC=CC=N5 |
| Reference | [1]. Yang Xu,et al. A credit-card library approach for disrupting protein-protein interactions. Bioorg Med Chem. 2006 Apr 15;14(8):2660-73. |
