O-Desmethyl Felodipine-d5

• CAT Number: R054172
• CAS Number: 1794827-40-9
• Molecular Formula: C17H17Cl2NO4
• Molecular Weight: 375.257
• Purity: ≥95%
• Synonyms: 1,4-Dihydro-2,6-dimethyl-5-(ethoxy-d5)carbonyl-4-(2,3-dichlorophenyl)-3-pyridinecarboxylic Acid; 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-Ethyl Ester-d5
• Storage: -20°C
• IUPAC Name: 4-(2,3-dichlorophenyl)-2,6-dimethyl-5-(1,1,2,2,2-pentadeuterioethoxycarbonyl)-1,4-dihydropyridine-3-carboxylic acid
• InChI: InChI=1S/C17H17Cl2NO4/c1-4-24-17(23)13-9(3)20-8(2)12(16(21)22)14(13)10-6-5-7-11(18)15(10)19/h5-7,14,20H,4H2,1-3H3,(H,21,22)/i1D3,4D2
• InChIKey: KCIBIAFYYVAYEO-SGEUAGPISA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])OC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)O)C)C

O-Desmethyl Felodipine-d5 is a deuterated analog of O-Desmethyl Felodipine, featuring five deuterium atoms. This high-purity isotopically labeled compound is vital for research in pharmacokinetics, drug metabolism, and cardiovascular pharmacology. O-Desmethyl Felodipine is a key metabolite of felodipine, a calcium channel blocker used in the treatment of hypertension. The deuterium labeling in O-Desmethyl Felodipine-d5 allows for precise quantification and tracking in biological samples, enhancing the accuracy of mass spectrometric analyses. This compound is particularly valuable for studying the metabolic pathways, efficacy, and safety profile of felodipine, making it an essential tool for researchers involved in drug development and therapeutic monitoring.