OAC1

• CAT Number: I003042
• CAS Number: 300586-90-7
• Molecular Formula: C14H11N3O
• Molecular Weight: 237.3
• Purity: ≥95%
• Synonyms: N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide
• Target: Transcription Factors
• Solubility: DMSO: ≥ 40 mg/mL
• Storage: Store at -20C
• InChIKey: HWJRIFZDXJKJJN-UHFFFAOYSA-N

OAC1 (CAT: I003042) is an Octamer-binding transcription factor 4 (Oct4)-activating compound. It has been shown to enhance the efficiency of induced pluripotent stem cell (iPSC) reprogramming and accelerate the reprogramming process. OAC1 promotes the expression and activity of Oct4, a key transcription factor in maintaining pluripotency and self-renewal of stem cells. By enhancing the Oct4 function, OAC1 facilitates the generation of iPSCs from somatic cells.

Reference

[1]. Li W, et al. Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20853-8.