OAC2

• CAT Number: I004262
• CAS Number: 6019-39-2
• Molecular Formula: C15H12N2O
• Molecular Weight: 236.3
• Purity: ≥95%
• Synonyms: N-(1H-indol-5-yl)benzamide
• Target: Oct3/4
• Solubility: DMSO: ≥ 2.4 mg/mL
• Storage: Room Temperature
• InChI: InChI=1S/C15H12N2O/c18-15(11-4-2-1-3-5-11)17-13-6-7-14-12(10-13)8-9-16-14/h1-10,16H,(H,17,18)
• InChIKey: JCAFGYWSIWYMOX-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C(=O)NC2=CC3=C(C=C2)NC=C3

OAC-2 is a chemical compound that activates the transcription factor 4 (OCT4) and improves the efficiency of induced pluripotent stem cell (iPSC) reprogramming. By enhancing OCT4’s activity, OAC-2 boosts the expression of genes involved in pluripotency and facilitates the generation of iPSCs. OAC-2 is therefore a valuable tool for stem cell research and regenerative medicine.

Reference

[1]. Li W, et al. Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20853-8.