For research use only. Not for therapeutic Use.
OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA)[1].
| Catalog Number | I033766 |
| CAS Number | 939825-12-4 |
| Synonyms | 1-[[2-[2-(4-bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride |
| Molecular Formula | C15H18BrClN2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H17BrN2O2.ClH/c16-14-3-1-13(2-4-14)5-6-15(19-9-10-20-15)11-18-8-7-17-12-18;/h1-4,7-8,12H,5-6,9-11H2;1H |
| InChIKey | YSOWYXRHOAXXTG-UHFFFAOYSA-N |
| SMILES | C1COC(O1)(CCC2=CC=C(C=C2)Br)CN3C=CN=C3.Cl |
| Reference | [1]. Alaoui-Jamali MA, et al. A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 2009;69(20):8017-8024. |
