For research use only. Not for therapeutic Use.
Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1].
Oct4 inducer-1 (compound OAC-3; 1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). Oct4 inducer-1 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies[1].
Oct4 inducer-1 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media[1].
| Catalog Number | R015453 |
| CAS Number | 182564-41-6 |
| Synonyms | 4-fluoro-N-(1H-indol-5-yl)benzamide |
| Molecular Formula | C15H11FN2O |
| Purity | ≥95% |
| InChI | InChI=1S/C15H11FN2O/c16-12-3-1-10(2-4-12)15(19)18-13-5-6-14-11(9-13)7-8-17-14/h1-9,17H,(H,18,19) |
| InChIKey | RQJUZWRDCVBOMH-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C(=O)NC2=CC3=C(C=C2)NC=C3)F |
| Reference | [1]. Hong SY, et, al. Enhancers of induced pluripotent stem cell reprogramming. US20140154805. |
