For research use only. Not for therapeutic Use.
ODN 1826 sodium (Cat No.: I040135) is a synthetic oligodeoxynucleotide (ODN) that acts as a toll-like receptor 9 (TLR9) agonist. By binding to TLR9, it stimulates innate immune responses, triggering the activation of immune cells such as dendritic cells and macrophages. ODN 1826 sodium is used in research to study immune modulation and as a potential adjuvant in vaccine development. Its ability to activate immune pathways makes it a candidate for boosting immune responses in infectious diseases, cancer immunotherapy, and autoimmune conditions.
| Purity | ≥95% |
| Reference | [1]. Hou Y, et al. Lipoamide Ameliorates Oxidative Stress via Induction of Nrf2/ARE Signaling Pathway in PC12 Cells. J Agric Food Chem. 2019 Jul 24;67(29):8227-8234. [2]. Qi XF, et al. CpG oligodeoxynucleotide induces apoptosis and cell cycle arrest in A20 lymphoma cells via TLR9-mediated pathways. Mol Immunol. 2013 Jul;54(3-4):327-37. [3]. Utaisincharoen P, et al. CpG ODN activates NO and iNOS production in mouse macrophage cell line (RAW 264.7). Clin Exp Immunol. 2002 Jun;128(3):467-73. |
