ODN 6016 sodium

• CAT Number: I040044
• Purity: ≥95%

ODN 6016 Sodium (Cat No.: I040044) is a synthetic oligodeoxynucleotide (ODN) designed to modulate immune responses by interacting with Toll-like receptors (TLRs), particularly TLR9. It is widely used in immunology and infectious disease research to study immune activation, inflammation, and antiviral mechanisms. The sodium salt form improves solubility and stability for in vitro and in vivo applications. ODN 6016 Sodium is valuable in vaccine development, autoimmune disease studies, and exploring novel therapeutic strategies for immune modulation and targeted immunotherapies.

Reference

[1]. Ries M, et al. Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation. J Leukoc Biol. 2013 Jul;94(1):123-35.
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[2]. Tennert K, et al. Elevated CD40 ligand silences α interferon production in an HIV-related immune reconstitution inflammatory syndrome. AIDS. 2013 Jan 14;27(2):297-9.
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