ODN INH 18 sodium

For research use only. Not for therapeutic Use.

  • CAT Number: I040298
  • Molecular Weight: 8275.00
  • Purity: ≥95%
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ODN INH-18 sodium is a linear 24-mer class B INH-ODN in which the 5′ INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 sodium showes inhibitory potency for TLR9 ligand-induced IFN-α production.


Catalog Number I040298
Purity ≥95%
Reference

[1]. Lenert P, Yasuda K, Busconi L, et al. DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo. Arthritis Res Ther. 2009;11(3):R79.
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