Ofloxacin-d8 Acyl-β-D-glucuronide(Mixture of Diastereomers)

• CAT Number: R052064
• CAS Number: NA
• Molecular Formula: C₂₄H₂₀D₈FN₃O₁₀
• Molecular Weight: 545.54
• Purity: ≥95%
• Synonyms: 1-[9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl-d8)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate] β-D-Glucopyranuronic Acid; DL-8280-d8 Glucuronide
• Storage: -20°C

Ofloxacin-d8 Acyl-β-D-glucuronide is a deuterium-labeled derivative of ofloxacin, a fluoroquinolone antibiotic, conjugated with β-D-glucuronic acid. The acyl-β-D-glucuronide form represents a phase II metabolite where the drug is conjugated to glucuronic acid for excretion. The deuterium labeling enhances its utility in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, allowing precise tracking and quantification of the drug metabolite in pharmacokinetic and metabolic studies. This labeled compound aids in understanding the drug’s metabolic pathways, optimizing dosing regimens, and studying potential drug interactions, contributing to more effective therapeutic strategies.