For research use only. Not for therapeutic Use.
Ofloxacin-d8 (CAS: 1219170-21-4), a premium pharmaceutical research compound designed for advanced antibacterial and antimicrobial studies. As a deuterated analog of Ofloxacin, it offers enhanced stability and improved pharmacokinetic properties. Ofloxacin-d8 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel antibacterial therapies. Trusted by leading laboratories, Ofloxacin-d8 is your go-to solution for cutting-edge antibacterial research. Unlock new possibilities in infection treatment with Ofloxacin-d8, where innovation meets reliability.
| Catalog Number | S000150 |
| CAS Number | 1219170-21-4 |
| Molecular Formula | C18H12D8FN3O4 |
| Purity | ≥95% |
| Target | Bacterial |
| IUPAC Name | 7-fluoro-2-methyl-6-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid |
| InChI | InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/i3D2,4D2,5D2,6D |
| InChIKey | GSDSWSVVBLHKDQ-SQUIKQQTSA-N |
| SMILES | [2H]C1(C(N(C(C(N1C)([2H])[2H])([2H])[2H])C2=C(C=C3C4=C2OCC(N4C=C(C3=O)C(=O)O)C)F)([2H])[2H])[2H] |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Todd PA, et al. Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use. Drugs. 1991 Nov;42(5):825-76. [3]. Smith JT, et al. Ofloxacin, a bactericidal antibacterial. Chemotherapy. 1991;37 Suppl 1:2-13. [4]. Olcay E, et al. Oral toxicity of pefloxacin, norfloxacin, ofloxacin and ciprofloxacin: comparison of biomechanical and histopathological effects on Achilles tendon in rats. J Toxicol Sci. 2011 Jun;36(3):339-45. |
