Ofloxacin N-Oxide Acetic Acid Salt (Mixture of Diastereomers)

• CAT Number: C000806
• CAS Number: 1216511-73-7
• Molecular Formula: C₂₀H₂₄FN₃O₇
• Molecular Weight: 437.42
• Purity: ≥95%
• Synonyms: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Acetic Acid Salt
• Solubility: DMSO (Very Slightly, Heated), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Light sensitive, Light sensitive
• IUPAC Name: acetic acid;7-fluoro-2-methyl-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
• InChI: InChI=1S/C18H20FN3O5.C2H4O2/c1-10-9-27-17-14-11(16(23)12(18(24)25)8-21(10)14)7-13(19)15(17)20-3-5-22(2,26)6-4-20;1-2(3)4/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H3,(H,3,4)
• InChIKey: WOXKVUYCBCCDTD-UHFFFAOYSA-N
• SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CC[N+](CC4)(C)[O-])F)C(=O)O.CC(=O)O

Ofloxacin N-Oxide Acetic Acid Salt (Cat No.:C000806) is a chemical mixture composed of diastereomers of ofloxacin N-oxide combined with acetic acid salt. Ofloxacin N-oxide is a derivative of ofloxacin, a fluoroquinolone antibiotic. The addition of acetic acid enhances solubility and stability. This compound mixture likely holds significance in pharmaceutical research, potentially influencing antibacterial properties, pharmacokinetics, and bioavailability.

Reference

Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 40, 581 (1991),