For research use only. Not for therapeutic Use.
Olacaftor, also known as VX-440, is a cystic fibrosis transmembrane regulator (CFTR) protein modulator.
| Catalog Number | I033840 |
| CAS Number | 1897384-89-2 |
| Synonyms | Olacaftor; VX-440; VX 440; VX440; |
| Molecular Formula | C29H34FN3O4S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | N-(benzenesulfonyl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide |
| InChI | InChI=1S/C29H34FN3O4S/c1-19(2)18-37-23-14-21(13-22(30)15-23)26-12-11-25(27(31-26)33-17-20(3)16-29(33,4)5)28(34)32-38(35,36)24-9-7-6-8-10-24/h6-15,19-20H,16-18H2,1-5H3,(H,32,34)/t20-/m0/s1 |
| InChIKey | NHOUNZMCSIHKHJ-FQEVSTJZSA-N |
| SMILES | O=C(C1=CC=C(C2=CC(OCC(C)C)=CC(F)=C2)N=C1N3C(C)(C)C[C@H](C)C3)NS(=O)(C4=CC=CC=C4)=O |
