For research use only. Not for therapeutic Use.
<ul><li><span style=/line-height: 1.53em; font-size: 13px;/>Oligomycin </span><span style=/line-height: 20px; font-size: 13px;/>(complex)</span><span style=/line-height: 1.53em; font-size: 13px;/>: a macrolide antibiotic that inhibits membrane bound mitochondrial ATPase. </span></li><li><span style=/line-height: 20px; font-size: 13px;/>Oligomycin (complex) is a </span><span style=/line-height: 1.53em; font-size: 13px;/>mixture of A, B, and C isomers.</span></li><li><span style=/line-height: 1.53em; font-size: 13px;/>The molecular weight and molecular structure shown on this page, are of Oligomycin A, the major component.</span></li><li><span style=/text-align: justify; line-height: 1.53em; font-size: 13px;/>HPLC shows </span><span style=/line-height: 20px; font-size: 13px;/>separately</span><span style=/line-height: 20px; font-size: 13px;/> </span><span style=/line-height: 1.53em; font-size: 13px;/>the concentrations of all components. Their ratio is not consistent and may vary from lot to lot. The analysis of the components is brought in CoA of particular lots.</span></li><li><span style=/text-align: justify; line-height: 1.53em; font-size: 13px;/>The three components are also offered as separate products.</span></li><li></li></ul>
Catalog Number | M046648 |
CAS Number | 1404-19-9 |
Purity | ≥95% |
Target | ATPase |
Solubility | Soluble in DMSO |
Storage | Store at -20C |
InChIKey | YQXULOWIGKNTBK-BKROBWKBSA-N |
Reference | Fitch, M. E., Chang, C., & Parslow, T. G. (2000). The BH3 domain is required for caspase-independent cell death induced by Bax and oligomycin. Cell Death and Differentiation, 7(4), 338-349. doi:10.1038/sj.cdd.4400659</span></p> |