For research use only. Not for therapeutic Use.
Oligomycin is an antibiotic and an inhibitor of ATP synthase, the enzyme responsible for ATP production in cells. It works by binding to the F0 subunit of ATP synthase in mitochondria, preventing the flow of protons across the mitochondrial membrane, thereby inhibiting ATP synthesis. Oligomycin is primarily used in laboratory research to study mitochondrial function and cellular energy production. While it has potential antimicrobial properties, its use is mainly restricted to experimental settings due to its potent effects on cellular respiration.
| Catalog Number | M046648 |
| CAS Number | 1404-19-9 |
| Purity | ≥95% |
| Target | Membrane Transporter/Ion Channel |
| Solubility | Soluble in DMSO |
| Storage | Store at -20C |
| InChIKey | YQXULOWIGKNTBK-BKROBWKBSA-N |
| SMILES | [Oligomycin] |
| Reference | Fitch, M. E., Chang, C., & Parslow, T. G. (2000). The BH3 domain is required for caspase-independent cell death induced by Bax and oligomycin. Cell Death and Differentiation, 7(4), 338-349. doi:10.1038/sj.cdd.4400659</span></p> |
