Olomoucine II

• CAT Number: I033858
• CAS Number: 500735-47-7
• Molecular Formula: C19H26N6O2
• Molecular Weight: 370.45
• Purity: 98%
• Synonyms: Olomoucine II; Olomoucine-II
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-[[[2-(1-hydroxybutan-2-ylamino)-9-propan-2-ylpurin-6-yl]amino]methyl]phenol
• InChI: InChI=1S/C19H26N6O2/c1-4-14(10-26)22-19-23-17(20-9-13-7-5-6-8-15(13)27)16-18(24-19)25(11-21-16)12(2)3/h5-8,11-12,14,26-27H,4,9-10H2,1-3H3,(H2,20,22,23,24)
• InChIKey: NDUVSANREQEDRE-UHFFFAOYSA-N
• SMILES: CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3O

Olomoucine II (Cat No.:I033858) is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). It specifically targets CDK1, CDK2, CDK5, and CDK7, which are involved in cell cycle regulation and other cellular processes. Olomoucine II inhibits the activity of CDKs by competing with ATP binding, leading to cell cycle arrest and inhibition of cell proliferation. This compound has been extensively used as a research tool to study cell cycle progression, cell growth, and CDK-related signaling pathways. It has also shown potential in anti-cancer research due to its ability to selectively target and inhibit CDKs involved in aberrant cell proliferation observed in cancer cells.

Reference

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