Olprinone Hydrochloride

• CAT Number: I000715
• CAS Number: 119615-63-3
• Molecular Formula: C14H11ClN4O
• Molecular Weight: 286.72
• Purity: ≥95%
• Synonyms: 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile;hydrochloride
• Target: Phosphodiesterase (PDE)
• Solubility: H2O: 6.8 mg/mL, DMSO: ＜ 4 mg/mL
• Storage: Store at -20°C
• InChI: InChI=1S/C14H10N4O.ClH/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10;/h2-6,8H,1H3,(H,17,19);1H
• InChIKey: PWTBMBAQRAOAFF-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl

Olprinone Hydrochloride(CAT: I000715) is a selective phosphodiesterase 3 (PDE3) inhibitor widely used in cardiovascular research. By increasing intracellular cyclic adenosine monophosphate (cAMP) levels, it enhances myocardial contractility and promotes vasodilation, making it valuable for studying heart failure and circulatory shock. Its dual inotropic and vasodilatory effects improve cardiac output and reduce vascular resistance, offering insights into therapeutic strategies for acute heart failure. Olprinone Hydrochloride is also employed in preclinical studies to investigate the molecular mechanisms of PDE3 inhibition and its role in cardiovascular modulation. Its high purity and efficacy make it a critical tool for advancing cardiovascular pharmacology research.