For research use only. Not for therapeutic Use.
Omadacycline Mesylate（Cat No.:I000717）is a modern tetracycline-class antibiotic designed to treat a variety of bacterial infections, including community-acquired bacterial pneumonia and skin infections. It works by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit, which blocks amino acid addition. Omadacycline is effective against both Gram-positive and Gram-negative bacteria, including strains resistant to traditional antibiotics, such as MRSA and certain Enterobacteriaceae. Its oral and intravenous formulations offer flexible dosing, making it a valuable option for outpatient and inpatient care. Omadacycline mesylate addresses rising antibiotic resistance, enhancing therapeutic options.
| Catalog Number | I000717 |
| CAS Number | 1196800-40-4 |
| Synonyms | (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-((neopentylamino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide methanesulfonate |
| Molecular Formula | C30H44N4O10S |
| Purity | ≥95% |
| Target | Antibiotic |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| IC50 | N/A |
| IUPAC Name | (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-9-[(2,2-dimethylpropylamino)methyl]-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;methanesulfonic acid |
| InChI | InChI=1S/C29H40N4O7.CH4O3S/c1-28(2,3)12-31-11-14-10-17(32(4)5)15-8-13-9-16-21(33(6)7)24(36)20(27(30)39)26(38)29(16,40)25(37)18(13)23(35)19(15)22(14)34;1-5(2,3)4/h10,13,16,21,31,34-35,38,40H,8-9,11-12H2,1-7H3,(H2,30,39);1H3,(H,2,3,4)/t13-,16-,21-,29-;/m0./s1 |
| InChIKey | BRTZQVQPPVIFKG-XGLFQKEBSA-N |
| SMILES | CC(C)(C)CNCC1=CC(=C2C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C.CS(=O)(=O)O |
| Reference | <p style=/line-height:25px/> |
