For research use only. Not for therapeutic Use.
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body/’s natural substances (serotonin) that causes vomiting.
CAS Number | 99614-02-5 |
Synonyms | 99614-02-5; Zofran; Zophren; Zudan; Zofran ODT |
Molecular Formula | C18H19N3O |
Purity | ≥95% |
Target | Neuronal Signaling |
Solubility | Limited solubility |
Storage | -20°C |
IUPAC Name | 9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one |
InChI | InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 |
InChIKey | FELGMEQIXOGIFQ-UHFFFAOYSA-N |
SMILES | CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C |
Reference | 1: Chu LF, Rico T, Cornell E, Obasi H, Encisco EM, Vertelney H, Gamble JG, <br> 3: Karacaer F, Biricik E, ünal İ, Büyükkurt S, ünlügenç H. Does prophylactic <br> 5: Fejzo MS, MacGibbon KW, Mullin PM. Critique of inaccurate reporting in 6: Gray JM, Maewal JD, Lunos SA, Furnival RA, Hendrickson MA. Ondansetron 7: Hagbom M, Novak D, Ekström M, Khalid Y, Andersson M, Lindh M, Nordgren J, 8: Green-Hopkins I, Monuteaux MC, Lee L, Nigrovic L, Mannix R, Schutzman S. Use 9: Ortiz-Gómez JR, Palacio-Abizanda FJ, Morillas-Ramirez F, Fornet-Ruiz I, 10: Hoffman RJ, Alansari K. Effect of intravenous ondansetron on QTc interval in |
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