ONO-0740556

• CAT Number: I042295
• CAS Number: 2250210-69-4
• Molecular Formula: C20H34NO6P
• Molecular Weight: 415.46
• Purity: ≥95%
• Synonyms: [(2R)-2-[5-(2-hexylphenyl)pentanoylamino]-3-hydroxypropyl] dihydrogen phosphate
• InChI: InChI=1S/C20H34NO6P/c1-2-3-4-5-10-17-11-6-7-12-18(17)13-8-9-14-20(23)21-19(15-22)16-27-28(24,25)26/h6-7,11-12,19,22H,2-5,8-10,13-16H2,1H3,(H,21,23)(H2,24,25,26)/t19-/m1/s1
• InChIKey: LYWONSBDWRVEKO-LJQANCHMSA-N
• SMILES: CCCCCCC1=CC=CC=C1CCCCC(=O)NC(CO)COP(=O)(O)O

ONO-0740556 is a potent Gi-coupled human lysophosphatidic acid receptor 1 (LPA1) agonist with an EC50 value of 0.26 nM[1].

Reference

[1]. Hiroaki Akasaka, et al. Structure of the active Gi-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun. 2022 Sep 15;13(1):5417.
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