For research use only. Not for therapeutic Use.
ONO-8711 dicyclohexylamine（Cat No.:I042395）is a selective and potent inhibitor of the p38 mitogen-activated protein kinase (MAPK) pathway, which plays a crucial role in inflammation and cell stress responses. It is used in preclinical research to investigate the role of p38 MAPK in various diseases, including autoimmune disorders, cancer, and neurodegenerative conditions. By inhibiting p38 MAPK, ONO-8711 dicyclohexylamine suppresses inflammatory cytokine production and modulates immune responses. This makes it a valuable tool for exploring potential therapies targeting inflammation, chronic diseases, and conditions linked to dysregulated p38 MAPK activity.
| Synonyms | (Z)-6-[(2R,3S)-3-[[(4-chloro-2-methylphenyl)sulfonylamino]methyl]-2-bicyclo[2.2.2]octanyl]hex-5-enoic acid;N-cyclohexylcyclohexanamine |
| Molecular Formula | C34H53ClN2O4S |
| Purity | ≥95% |
| IUPAC Name | (Z)-6-[(2R,3S)-3-[[(4-chloro-2-methylphenyl)sulfonylamino]methyl]-2-bicyclo[2.2.2]octanyl]hex-5-enoic acid;N-cyclohexylcyclohexanamine |
| InChI | InChI=1S/C22H30ClNO4S.C12H23N/c1-15-13-18(23)11-12-21(15)29(27,28)24-14-20-17-9-7-16(8-10-17)19(20)5-3-2-4-6-22(25)26;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h3,5,11-13,16-17,19-20,24H,2,4,6-10,14H2,1H3,(H,25,26);11-13H,1-10H2/b5-3-;/t16?,17?,19-,20-;/m0./s1 |
| InChIKey | LLFSWESJGDSALX-YBAOTWTCSA-N |
| SMILES | CC1=C(C=CC(=C1)Cl)S(=O)(=O)NC[C@@H]2[C@H](C3CCC2CC3)/C=C\CCCC(=O)O.C1CCC(CC1)NC2CCCCC2 |
