For research use only. Not for therapeutic Use.
Ophiobolin A is the dominant member of a class of phytotoxic metabolites produced by plant pathogenic fungi.</br>Ophiobolin A acts by inhibiting calmodulin action in calcium regulation.
| Catalog Number | R002154 |
| CAS Number | 4611-05-6 |
| Synonyms | (2/’S,3/’S,3aR,5/’R,6aS,9R,9aS,10aR)-1,3a,4,4/’,5/’,6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3/’,9,10a-trimethyl-5/’-spiro[dicyclopenta[a,d]cyclooctene-3(2H),2/'(3/’H)-furan]-6-carboxaldehyde |
| Molecular Formula | C25H36O4 |
| Purity | ≥95% |
| Target | Phosphodiesterase (PDE) |
| Solubility | Soluble in DMSO |
| Storage | -20°C |
| InChIKey | MWYYLZRWWNBROW-BDZRSQQBSA-N |
| Reference | Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis. Quetglas S. EMBO J. 2002, 21, 3970.<br/><br/>The biology of ophiobolins. Au T.K. et al. Life Sci. 2000, 67, 733. (Review)</span></p> |
