For research use only. Not for therapeutic Use.
Opnurasib (JDQ-443,NVP-JDQ443) , a potent and selective, orally bioavailable covalent inhibitor of GDP-bound KRASG12C with an IC50 of 0.012 µM for inhibition of c-Raf recruitment.
| Catalog Number | I047392 |
| CAS Number | 2653994-08-0 |
| Molecular Formula | C29H28CIN7O |
| Purity | ≥95% |
| Reference | [1] Weiss A, et al. Cancer Discov. 2022 Jun 2;12(6):1500-1517. |
