For research use only. Not for therapeutic Use.
Osaterone (Cat No.: I033984) is a steroidal anti-androgen primarily used in veterinary medicine to treat benign prostatic hyperplasia (BPH) in male dogs. It functions by inhibiting the effects of androgens on the prostate, reducing its size and alleviating urinary symptoms. Osaterone competes with dihydrotestosterone (DHT) for androgen receptor binding while also suppressing testosterone synthesis. Unlike other anti-androgens, it has a long-lasting effect with minimal side effects. Its efficacy and safety make it a preferred choice for managing prostate disorders in veterinary practice.
CAS Number | 105149-04-0 |
Synonyms | Osaterone |
Molecular Formula | C20H25ClO4 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | ( )-6-Chloro-17-hydroxy-2-oxapregna-4,6-diene-3,20-dione |
InChI | InChI=1S/C20H25ClO4/c1-11(22)20(24)7-5-14-12-8-16(21)15-9-17(23)25-10-18(15,2)13(12)4-6-19(14,20)3/h8-9,12-14,24H,4-7,10H2,1-3H3/t12-,13+,14+,18-,19+,20+/m1/s1 |
InChIKey | ZLLOIFNEEWYATC-XMUHMHRVSA-N |
SMILES | CC([C@@]1(O)CC[C@@]2([H])[C@]3([H])C=C(Cl)C4=CC(OC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O |
Reference | 1: Albouy M, Sanquer A, Maynard L, Eun HM. Efficacies of osaterone and delmadinone in the treatment of benign prostatic hyperplasia in dogs. Vet Rec. 2008 Aug 9;163(6):179-83. PubMed PMID: 18689779. |