Oseltamivir acid methyl ester

• CAT Number: I043378
• CAS Number: 208720-71-2
• Molecular Formula: C15H26N2O4
• Molecular Weight: 298.38
• Purity: ≥95%
• Synonyms: methyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate
• InChI: InChI=1S/C15H26N2O4/c1-5-11(6-2)21-13-8-10(15(19)20-4)7-12(16)14(13)17-9(3)18/h8,11-14H,5-7,16H2,1-4H3,(H,17,18)/t12-,13+,14+/m0/s1
• InChIKey: HQFJHRGEFIDLDI-BFHYXJOUSA-N
• SMILES: CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OC

Oseltamivir acid methyl ester is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid by carboxylesterase 1 (CES1)[1].

Reference

[1]. Mai Shimizu, et al. Systematic Approach for Screening of Prodrugs: Evaluation Using Oseltamivir Analogues as Models. J Pharm Sci. 2021 Feb;110(2):925-934.
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