Oseltamivir Phosphate

For research use only. Not for therapeutic Use.

  • CAT Number: A000321
  • CAS Number: 204255-11-8
  • Molecular Formula: C16H28N2O4 • H3PO4
  • Molecular Weight: 410.40
  • Purity: ≥95%
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Oseltamivir Phosphate(Cat No.:A000321)is an antiviral drug used in the treatment and prevention of influenza A and B infections. It inhibits the neuraminidase enzyme, preventing the release of new viral particles from infected cells, thereby reducing the spread of the virus. Oseltamivir is most effective when administered within 48 hours of the onset of symptoms. It is commonly prescribed for patients with influenza or for prophylactic use in individuals exposed to the virus. Oseltamivir is available in oral form, typically as capsules or suspension.


Catalog Number A000321
CAS Number 204255-11-8
Synonyms

NA

Molecular Formula C16H28N2O4 • H3PO4
Purity ≥95%
Target Influenza Virus
Solubility Limited solubility
Storage 3 years -20C powder
Overview of Clinical Research

<span style=”color:#000000;”><span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>Oseltamivir is a&nbsp;Neuraminidase inhibitor. It is marketed in&nbsp;Influenza virus infections.</span></span></span>

IUPAC Name ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate;phosphoric acid
InChI InChI=1S/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/m0./s1
InChIKey PGZUMBJQJWIWGJ-ONAKXNSWSA-N
SMILES CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O
Reference

<span style=”color:#000000;”><span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>1.Huang, Hua, et al. &quot;Transplacental transfer of oseltamivir phosphate and its metabolite oseltamivir carboxylate using the ex vivo human placenta perfusion model in Chinese Hans population.&quot;&nbsp;<i style=”font-family: Arial, sans-serif; font-size: 13px;”>The Journal of Maternal-Fetal &amp; Neonatal Medicine</i>&nbsp;30.11 (2017): 1288-1292.<br />
2.de Oliveira, Joana T., et al. &quot;Anti-influenza neuraminidase inhibitor oseltamivir phosphate induces canine mammary cancer cell aggressiveness.&quot;&nbsp;<i style=”font-family: Arial, sans-serif; font-size: 13px;”>PloS one</i>&nbsp;10.4 (2015): e0121590.<br />
3.Li, Ping, et al. &quot;A simple and robust approach for evaluation of antivirals using a recombinant influenza virus expressing Gaussia luciferase.&quot;&nbsp;<i style=”font-family: Arial, sans-serif; font-size: 13px;”>Viruses</i>&nbsp;10.6 (2018): 325.</span></span></span>

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