For research use only. Not for therapeutic Use.
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.<br>OSMI-4 (4b) is the best OGT inhibitor reported to date, with a ∼3 μM EC50 in cells, making it especially attractive for probing OGT’s complex biology[1].
| Catalog Number | I019657 |
| CAS Number | 2260791-14-6 |
| Molecular Formula | C₂₇H₂₆ClN₃O₇S₂ |
| Purity | ≥95% |
| Target | Acyltransferase |
| Reference | [1]. Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545. |
