Otenabant (CP-945598) HCl

• CAT Number: I008514
• CAS Number: 686347-12-6
• Molecular Formula: C25H25Cl2N7O.HCl
• Molecular Weight: 546.88
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N.Cl

Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1.

Reference

[1] Griffith DA, et al. J Med Chem, 2009, 52(2), 234-237.
[2] Hadcock JR, et al. Biochem Biophys Res Commun, 2010, 394(2), 366-371.