For research use only. Not for therapeutic Use.
OTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335)[1].
| Catalog Number | I044035 |
| CAS Number | 1356943-67-3 |
| Synonyms | 1-[6-(3-chloro-4-hydroxyphenyl)-4-[[4-(diethylamino)cyclohexyl]amino]quinolin-3-yl]ethanone |
| Molecular Formula | C27H32ClN3O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H32ClN3O2/c1-4-31(5-2)21-10-8-20(9-11-21)30-27-22-14-18(19-7-13-26(33)24(28)15-19)6-12-25(22)29-16-23(27)17(3)32/h6-7,12-16,20-21,33H,4-5,8-11H2,1-3H3,(H,29,30) |
| InChIKey | OSRDFHWWFIEYDB-UHFFFAOYSA-N |
| SMILES | CCN(CC)C1CCC(CC1)NC2=C3C=C(C=CC3=NC=C2C(=O)C)C4=CC(=C(C=C4)O)Cl |
| Reference | [1]. Yo Matsuo, et al. Quinoline derivatives and melk inhibitors containing the same. WO2012016082A1. |
