Ouabain Octahydrate

• CAT Number: I000419
• CAS Number: 11018-89-6
• Molecular Formula: C29H60O20
• Molecular Weight: 728.77
• Purity: ≥95%
• Target: Autophagy
• Solubility: DMSO：≥ 35 mg/mL
• Storage: store -20℃
• IUPAC Name: 3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one;octahydrate
• InChI: 1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-;;;;;;;;/m0......../s1
• InChIKey: TYBARJRCFHUHSN-DMJRSANLSA-N
• SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O.O.O.O.O.O.O.O.O

Ouabain Octahydrate is a cardiac glycoside widely used in research to study cardiac physiology and ion transport. It specifically inhibits the Na⁺/K⁺-ATPase pump, leading to increased intracellular sodium and calcium levels, which enhance cardiac contractility. Ouabain serves as a critical tool for investigating heart failure mechanisms, arrhythmias, and signal transduction pathways. Additionally, it is studied for its potential role in cancer research and as an endogenous hormone-like compound. Its precise mechanism makes it invaluable in cardiovascular and cellular physiology studies.