Ouabain Octahydrate

• CAT Number: I000419
• CAS Number: 11018-89-6
• Molecular Formula: C29H60O20
• Molecular Weight: 728.77
• Purity: ≥95%
• Target: Others
• Solubility: DMSO：≥ 35 mg/mL
• Storage: 3 years -20C powder

Ouabain Octahydrate (Cat.No:I000419) is a natural compound derived from the African plant Strophanthus gratus. It acts as a cardiac glycoside, specifically inhibiting the Na+/K+-ATPase pump in cells. Ouabain Octahydrate has been used in research to study its effects on ion transport, cell signaling, and cardiovascular physiology.

Reference

[1]. Lucchesi, P.A. and K.J. Sweadner, Postnatal changes in Na,K-ATPase isoform expression in rat cardiac ventricle. Conservation of biphasic ouabain affinity. J Biol Chem, 1991. 266(14): p. 9327-31.
[2]. Juhaszova, M. and M.P. Blaustein, Na+ pump low and high ouabain affinity alpha subunit isoforms are differently distributed in cells. Proc Natl Acad Sci U S A, 1997. 94(5): p. 1800-5.
[3]. Hosoi, R., et al., Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes. J Neurochem, 1997. 69(5): p. 2189-96.
[4]. Nelissen-Vrancken, H.J., et al., Ouabain improves cardiac function in vivo in rats with heart failure after chronic but not acute treatment. Naunyn Schmiedebergs Arch Pharmacol, 1997. 356(2): p. 203-9.