For research use only. Not for therapeutic Use.
Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma[1].
Oxelumab (10 μg/mL; 3 d) represses cell proliferation of NK cells[2].
Oxelumab (5 and 30 mg/kg; i.p., once daily for twice) affects the concentrations of IL-6 and the frequencies of splenic human effector memory T cells and switched B cells[1].
| Catalog Number | I042191 |
| CAS Number | 1186098-83-8 |
| Purity | ≥95% |
| Reference | [1]. Youngblood BA, et al. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019;180(2):91-102. [2]. Kweon S, et al. Expansion of Human NK Cells Using K562 Cells Expressing OX40 Ligand and Short Exposure to IL-21. Front Immunol. 2019 Apr 24;10:879. |
