For research use only. Not for therapeutic Use.
OXi8007 is a water-soluble phosphate proagent of OXi8006, a tubulin-binding compound.
| Catalog Number | I008523 |
| CAS Number | 288847-41-6 |
| Synonyms | disodium;[2-methoxy-5-[6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-2-yl]phenyl] phosphate |
| Molecular Formula | C26H24NNa2O10P |
| Purity | ≥95% |
| InChI | InChI=1S/C26H26NO10P.2Na/c1-32-16-7-8-17-18(13-16)27-24(14-6-9-19(33-2)20(10-14)37-38(29,30)31)23(17)25(28)15-11-21(34-3)26(36-5)22(12-15)35-4;;/h6-13,27H,1-5H3,(H2,29,30,31);;/q;2*+1/p-2 |
| InChIKey | GQIZTUAJGVBAFG-UHFFFAOYSA-L |
| SMILES | COC1=CC2=C(C=C1)C(=C(N2)C3=CC(=C(C=C3)OC)OP(=O)([O-])[O-])C(=O)C4=CC(=C(C(=C4)OC)OC)OC.[Na+].[Na+] |
| Reference | [1]. Strecker TE, et al. The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts. Cancer Lett. 2015 Dec 1;369(1):229-41. |
