For research use only. Not for therapeutic Use.
Oxidized ATP trisodium salt (OxATP)(CAT: I040799) is an irreversible antagonist of P2X purinergic receptors, particularly P2X7. It is commonly used in immunology and neurobiology research to study ATP-mediated signaling pathways. By covalently modifying the receptor, OxATP inhibits ATP-induced responses such as cytokine release, cell proliferation, and apoptosis. It plays a crucial role in exploring inflammation, immune cell regulation, and pain signaling. The trisodium salt form offers excellent water solubility and stability for in vitro and in vivo applications. Oxidized ATP trisodium salt is a valuable tool for investigating purinergic receptor functions and developing therapeutic strategies targeting P2X7-related diseases.
| CAS Number | 71997-40-5 |
| Synonyms | trisodium;[[[(2R)-2-[(1R)-1-(6-aminopurin-9-yl)-2-oxoethoxy]-3-oxopropoxy]-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate |
| Molecular Formula | C10H11N5Na3O13P3 |
| Purity | ≥95% |
| IUPAC Name | trisodium;[[[(2R)-2-[(1R)-1-(6-aminopurin-9-yl)-2-oxoethoxy]-3-oxopropoxy]-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate |
| InChI | InChI=1S/C10H14N5O13P3.3Na/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;/q;3*+1/p-3/t6-,7+;;;/m0.../s1 |
| InChIKey | FONDUACPXCWSBT-PXJNTPRPSA-K |
| SMILES | C1=NC(=C2C(=N1)N(C=N2)C(C=O)OC(COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])C=O)N.[Na+].[Na+].[Na+] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
