For research use only. Not for therapeutic Use.
Oxotremorine sesquifumarate is a mAChR agonist that mainly activates M2 receptors. Oxotremorine sesquifumarate can be used for neurological research[1][2].
Oxotremorine (10.5 μM) produces a paralytic effect on twitch responses of rat diaphragm in vitro to direct and indirect stimulation[1].
In rats with sciatic nerve injuries, Oxotremorine (10, 5, 2 1 μg; 10 μL) i.t. dose-dependently suppresses the tactile hypersensitivity[2].
| Catalog Number | M080437 |
| CAS Number | 17360-35-9 |
| Molecular Formula | C16H22N2O5 |
| Purity | ≥95% |
| Reference | [1]. M Das, D K Ganguly, et al. Enhancement by oxotremorine of acetylcholine release from the rat phrenic nerve. Br J Pharmacol. 1978 Feb;62(2):195-8. [2]. Zhiyang Song, et al. Muscarinic receptor activation potentiates the effect of spinal cord stimulation on pain-related behavior in rats with mononeuropathy. Neurosci Lett. 2008 May 2;436(1):7-12. |
