For research use only. Not for therapeutic Use.
AEA acts as an endogenous mimic of Δ oxy-<wbr></wbr>AEA is the O-<wbr></wbr>alkyl-<wbr></wbr>N-<wbr></wbr>acyl oxyhomologue of AEA. oxy-<wbr></wbr>AEA is selective for the peripheral cannabinoid (CB<sub>2</sub>) receptor with K<sub>i</sub> values of 0.47 and 0.081 µM for hCB<sub>1</sub> and hCB<sub>2</sub>, respectively. In comparison, AEA has a greater affinity for the central cannabinoid (CB<sub>1</sub>) receptor with K<sub>i</sub> values of 0.07 and 0.18 µM for hCB<sub>1</sub> and hCB<sub>2</sub>, respectively. oxy-<wbr></wbr>AEA is the first known fatty acid amide with a reversed CB<sub>1</sub>/CB<sub>2</sub> affinity ratio.
| Catalog Number | R024831 |
| CAS Number | 883296-70-6 |
| Synonyms | oxy-AEA;oxy-Anandamide |
| Molecular Formula | C22H37NO3 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (5Z,8Z,11Z,14Z)-N-(2-hydroxyethoxy)icosa-5,8,11,14-tetraenamide |
| InChI | InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-26-21-20-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15- |
| InChIKey | ANMKTCMIIFBOGG-DOFZRALJSA-N |
| SMILES | CCCCCC=CCC=CCC=CCC=CCCCC(=O)NOCCO |
| Reference | 1.Devane, W.A.,Hanus, L.,Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949 (1992). |
