For research use only. Not for therapeutic Use.
Oxytetracycline Dihydrate（Cat No.:A000446）is a broad-spectrum tetracycline antibiotic widely used to combat bacterial infections in humans, animals, and plants. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, blocking the addition of amino acids and thus halting bacterial growth. Known for its effectiveness against a range of gram-positive and gram-negative bacteria, oxytetracycline is utilized in treating respiratory, urinary, and skin infections. Its stable dihydrate form enhances solubility and stability, making it valuable in pharmaceutical formulations, veterinary medicine, and agricultural applications for managing bacterial diseases.
| Catalog Number | A000446 |
| CAS Number | 6153-64-6 |
| Synonyms | NA |
| Molecular Formula | C22H28N2O11 |
| Purity | ≥95% |
| Storage | 3 years -20C powder |
| IUPAC Name | (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;dihydrate |
| InChI | InChI=1S/C22H24N2O9.2H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);2*1H2/t12-,13-,14+,17+,21-,22+;;/m1../s1 |
| InChIKey | IMLJLCJZQLGHJS-JEKSYDDFSA-N |
| SMILES | C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.O.O |
| Reference | <p>Chopra, Ian, and Marilyn Roberts. /Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance./ <em>Microbiology and Molecular Biology Reviews</em> (2001): 232-60. <em>Http://www.ncbi.nlm.nih.gov</em>. Web. 21 Aug. 2012.</p><p>Hubbard A.R., 2011, Evaluation of Kasugamycin-use strategies Designed to Delay Development of Resistance in Erwinia amylovora. Master thesis of Botany and Plant Pathology, Oregon state University.</p></span></p> |
