Oxytocin, deamino-6-carba-

• CAT Number: I034106
• CAS Number: 30927-32-3
• Molecular Formula: C44H67N11O12S
• Molecular Weight: 974.14
• Purity: 98%
• Synonyms: Oxytocin, deamino-6-carba-; beta-Deaminocystathionine-oxytocin; Deamino-6-carbaoxytocin.
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (2S)-1-((4S,7S,10S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-((S)-sec-butyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-((2-amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
• InChI: InChI=1S/C44H67N11O12S/c1-5-24(4)37-43(66)50-27(12-13-33(45)57)39(62)52-31(21-34(46)58)40(63)51-28(14-17-68-18-15-36(60)49-30(41(64)54-37)20-25-8-10-26(56)11-9-25)44(67)55-16-6-7-32(55)42(65)53-29(19-23(2)3)38(61)48-22-35(47)59/h8-11,23-24,27-32,37,56H,5-7,12-22H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,60)(H,50,66)(H,51,63)(H,52,62)(H,53,65)(H,54,64)/t24-,27-,28-,29-,30-,31-,32-,37?/m0/s1
• InChIKey: MRNKEVGKBFIFET-AHCPCVRLSA-N
• SMILES: CC[C@H](C)C1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCSCCC(=O)N[C@H](C(=O)N1)Cc2ccc(cc2)O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N

Deamino-6-carba-oxytocin (CAT: I034106) is a potent oxytocin analog designed for enhanced stability against enzymatic degradation, making it resistant to physiologically significant enzymatic systems such as oxytocinase. It retains high affinity for oxytocin receptors, eliciting similar biological effects to natural oxytocin, including uterotonic and antidiuretic activities. dC60 is widely utilized in pharmacological and biochemical research for studying oxytocin receptor-mediated signaling, particularly in reproductive physiology, labor induction, and social bonding behaviors. Its enzymatic resistance and potency make it a valuable tool for exploring therapeutic applications where prolonged oxytocin activity is beneficial, such as in labor management and neuropsychiatric disorders.