For research use only. Not for therapeutic Use.
Ozagrel is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.<br>Ozagrel prevents oleic acid (OA)-induced thromboxane A(2) generation and subsequently increased total protein concentration and the numbers of macrophages and neutrophils in bronchoalveolar lavage fluid and increases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression in the whole lung of guinea pigs.
| Catalog Number | A000356 |
| CAS Number | 82571-53-7 |
| Synonyms | OKY-046 |
| Molecular Formula | C13H12N2O2 |
| Purity | ≥95% |
| Target | Factor Xa |
| Solubility | >10.8mg/mL in DMSO |
| Storage | 3 years -20C powder |
| InChIKey | SHZKQBHERIJWAO-AATRIKPKSA-N |
