p-Fluorophenylalanine

• CAT Number: I034542
• CAS Number: 51-65-0
• Molecular Formula: C9H10FNO2
• Molecular Weight: 183.1824
• Purity: 98%
• Synonyms: p-Fluorophenylalanine; p Fluorophenylalanine; 4-Fluorophenylalanine; 4 Fluorophenylalanine; 4-Fluoro-dl-para-phenylalanine; NSC 71433; NSC71433; NSC-71433
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-amino-3-(4-fluorophenyl)propanoic acid
• InChI: InChI=1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
• InChIKey: XWHHYOYVRVGJJY-UHFFFAOYSA-N
• SMILES: NC(C(O)=O)Cc1ccc(F)cc1

p-Fluorophenylalanine inhibits mitosis and reversibly arrests HeLa cells in G2. p-Fluoro-DL-phenylalanine (pFPhe), a toxic antimetabolite, is a racemic mixture of a substituted (halogenated) benzoyl D and L phenylalanine useful as a selection marker for wine yeast transformation and with potential use in endomorphin, antiviral, and antimicrobial drug development. Phenylalanine analogue, rho-fluorophenylalanine (pFPhe) is also used to induce apoptosis.

Reference

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