p-MPPF dihydrochloride

• CAT Number: I034900
• CAS Number: 223699-41-0
• Molecular Formula: C25H27FN4O2.2HCl
• Molecular Weight: 525.66
• Purity: ≥95%
• IUPAC Name: 4-fluoro-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylbenzamide;dihydrochloride
• InChI: InChI=1S/C25H27FN4O2.2ClH/c1-32-23-7-3-2-6-22(23)29-17-14-28(15-18-29)16-19-30(24-8-4-5-13-27-24)25(31)20-9-11-21(26)12-10-20;;/h2-13H,14-19H2,1H3;2*1H
• SMILES: COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4=CC=C(C=C4)F.Cl.Cl

Selective 5-HT1A antagonist, more potent than p-MPPI (Axon 1091).
KEYWORDS: p-MPPF dihydrochloride | supplier | 5-HT1A antagonist | MPPF | CAS [155204-26-5] | Serotonin | 5-HT1A | Antagonist | Receptors

Reference

Thielen et al. 4-(2′-Methoxyphenyl)-1-[2′-[N-(2′′-pyridinyl)-p-iodo-benzamido]ethyl]piperazine and p-fluorobenzamido]ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors. J. Pharmacol. Exp. Ther. 1996, 277, 661.