p-NH2-Bn-DOTA(B-200)

• CAT Number: M131909
• CAS Number: 181065-46-3
• Molecular Formula: C23H35N5O8
• Molecular Weight: 509.56
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 2-[6-[(4-aminophenyl)methyl]-4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
• InChI: InChI=1S/C23H35N5O8/c24-18-3-1-17(2-4-18)11-19-12-27(15-22(33)34)8-7-25(13-20(29)30)5-6-26(14-21(31)32)9-10-28(19)16-23(35)36/h1-4,19H,5-16,24H2,(H,29,30)(H,31,32)(H,33,34)(H,35,36)
• InChIKey: VEYDUAGNNSZVTN-UHFFFAOYSA-N
• SMILES: C1CN(CCN(C(CN(CCN1CC(=O)O)CC(=O)O)CC2=CC=C(C=C2)N)CC(=O)O)CC(=O)O

p-NH2-Bn-DOTA (B-200)(CAT: M131909) is a derivative of DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), which is a macrocyclic chelating agent used extensively in radiopharmaceuticals and diagnostic imaging. The p-NH2-Bn modification refers to the presence of a para-amino benzyl group, which allows for further functionalization or conjugation with biomolecules, such as peptides or antibodies, for targeted imaging or therapy. DOTA derivatives, like p-NH2-Bn-DOTA, are crucial in radiolabeling because they form stable complexes with metal ions like gadolinium, indium, or yttrium, making them ideal for use in MRI contrast agents or targeted radioisotope therapies in cancer treatment.