For research use only. Not for therapeutic Use.
<em>p</em>-Nitrobenzyl mesylate (PNBM) is a reagent that is used to alkylate thiophosphates, forming thiophosphate ester epitopes that can be recognized by specific antibodies. Substrates phosphorylated with adenosine 5/’-(γ-thio)-triphosphate (ATPγS; Item No. <span class=/itemid/>14957</span>) or N The tagged substrates can be isolated by immunoprecipitation or immunoaffinity purification, or they can be detected by immunoblotting.
| Catalog Number | R066937 |
| CAS Number | 39628-94-9 |
| Synonyms | 4-Nitrobenzyl mesylate;para-Nitrobenzyl mesylate;PNBM |
| Molecular Formula | C8H9NO5S |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (4-nitrophenyl)methyl methanesulfonate |
| InChI | InChI=1S/C8H9NO5S/c1-15(12,13)14-6-7-2-4-8(5-3-7)9(10)11/h2-5H,6H2,1H3 |
| InChIKey | QZIYKAFPHRTIAI-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)OCC1=CC=C(C=C1)[N+](=O)[O-] |
| Reference | 1.Allen, J.J.,Li, M.,Brinkworth, C.S., et al. A semisynthetic epitope for kinase substrates. Nat. Methods 4(6), 511-516 (2007). |
