For research use only. Not for therapeutic Use.
Prodrug of P2Y14 receptor antagonist PPTN (Axon 3420); highly bioavailable.
KEYWORDS: P2Y14 Antagonist Prodrug 7j hydrochloride | supplier | PPTN Prodrug 7j | 1315308-19-0 | 1315308-19-0 | Axon 1958 | P2Y14 antagonist | Axon Ligands | P2Y14
| Catalog Number | I047581 |
| CAS Number | 1315308-19-0 |
| Molecular Formula | C33H31F3N2O3.HCl |
| Purity | ≥95% |
| IUPAC Name | [2-(dimethylamino)-2-oxoethyl] 4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylate;hydrochloride |
| InChI | InChI=1S/C33H31F3N2O3.ClH/c1-38(2)31(39)20-41-32(40)27-18-26-17-25(22-7-10-28(11-8-22)33(34,35)36)9-12-29(26)30(19-27)24-5-3-21(4-6-24)23-13-15-37-16-14-23;/h3-12,17-19,23,37H,13-16,20H2,1-2H3;1H |
| SMILES | CN(C)C(=O)COC(=O)C1=CC(=C2C=CC(=CC2=C1)C3=CC=C(C=C3)C(F)(F)F)C4=CC=C(C=C4)C5CCNCC5.Cl |
| Reference | J Robichaud et al. Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y(14). Bioorg. Med. Chem. Lett. 2011, 21(14), 4366-4368. |
