p38 MAPK-IN-4

• CAT Number: R065607
• CAS Number: 219138-24-6
• Molecular Formula: C20H13ClFN3O
• Molecular Weight: 365.79
• Purity: ≥95%
• Synonyms: 2-(4-chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1H-pyrazol-3-one
• InChI: InChI=1S/C20H13ClFN3O/c21-15-3-7-17(8-4-15)25-20(26)18(13-1-5-16(22)6-2-13)19(24-25)14-9-11-23-12-10-14/h1-12,24H
• InChIKey: DZFBYHUKZSRPHU-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C2=C(NN(C2=O)C3=CC=C(C=C3)Cl)C4=CC=NC=C4)F

p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM[1].

Reference

[1]. S E de Laszlo, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94.
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