For research use only. Not for therapeutic Use.
p53-MDM2-IN-1 (Example 30) is an inhibitor of p53-MDM2/X protein interaction with an Ki value of 23.35 µM. p53-MDM2-IN-1 can be used for anti-tumor research[1].
| Catalog Number | I041453 |
| CAS Number | 381717-91-5 |
| Synonyms | (4E)-5-(4-chlorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(3-imidazol-1-ylpropyl)pyrrolidine-2,3-dione |
| Molecular Formula | C23H20ClN3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C23H20ClN3O3/c24-18-9-7-16(8-10-18)20-19(21(28)17-5-2-1-3-6-17)22(29)23(30)27(20)13-4-12-26-14-11-25-15-26/h1-3,5-11,14-15,20,28H,4,12-13H2/b21-19+ |
| InChIKey | JBSITHXZPKMWGY-XUTLUUPISA-N |
| SMILES | C1=CC=C(C=C1)C(=C2C(N(C(=O)C2=O)CCCN3C=CN=C3)C4=CC=C(C=C4)Cl)O |
| Reference | [1]. Zhang W, et al. Pyrrylketone compound and application thereof as drug. China. CN102603717. |
