Paclitaxel-d5 (Benzoyloxy)

• CAT Number: R046691
• CAS Number: 1261254-56-1
• Molecular Formula: C47H51NO14
• Molecular Weight: 858.94
• Purity: ≥95%
• Synonyms: Abraxane-d5; Genaxol-d5; Genetaxyl-d5; OncoGel-d5; Onxal-d5; Pacliex-d5; (-)-Paclitaxel-d5; Taxol-d5; Yewtaxan-d5; NSC 125973-d5
• Storage: -20°C
• IUPAC Name: [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] 2,3,4,5,6-pentadeuteriobenzoate
• InChI: InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1/i9D,14D,15D,20D,21D
• InChIKey: RCINICONZNJXQF-IRNQFUICSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])C(=O)O[C@H]2[C@H]3[C@@]([C@H](C[C@@H]4[C@]3(CO4)OC(=O)C)O)(C(=O)[C@@H](C5=C([C@H](C[C@@]2(C5(C)C)O)OC(=O)[C@@H]([C@H](C6=CC=CC=C6)NC(=O)C7=CC=CC=C7)O)C)OC(=O)C)C)[2H])[2H]

Paclitaxel-d5 (Benzoyloxy)（Cat No.:R046691）is a deuterated derivative of paclitaxel, a widely used chemotherapeutic agent known for its ability to stabilize microtubules and inhibit cell division. The incorporation of five deuterium atoms enhances its isotopic labeling, making it valuable for pharmacokinetic studies and metabolic investigations. This compound retains the therapeutic properties of paclitaxel while allowing researchers to trace its metabolic pathways and interactions in biological systems. Paclitaxel-d5 (Benzoyloxy) is particularly useful in drug development and pharmacological research, offering insights into the compound’s efficacy and mechanisms of action in cancer therapy.