Palbociclib-SMCC

• CAT Number: I008547
• CAS Number: N/A
• Molecular Formula: C36H42N8O5
• Molecular Weight: 666.78
• Purity: ≥95%
• Synonyms: PD0332991-SMCC; PD 0332991-SMCC; PD-0332991-SMCC; Palbociclib-SMCC; Palbociclib-SMCC linker; Palbociclib with a SMCC linker. Palbociclib conjugate.;1-((4-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyrid
• Target: CDK inhibitor
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: 1-[[4-[4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carbonyl]cyclohexyl]methyl]pyrrole-2,5-dione
• InChI: InChI=1S/C36H42N8O5/c1-22-28-20-38-36(40-33(28)44(26-5-3-4-6-26)35(49)32(22)23(2)45)39-29-12-11-27(19-37-29)41-15-17-42(18-16-41)34(48)25-9-7-24(8-10-25)21-43-30(46)13-14-31(43)47/h11-14,19-20,24-26H,3-10,15-18,21H2,1-2H3,(H,37,38,39,40)
• InChIKey: YPPDYAQBRIHIAI-UHFFFAOYSA-N
• SMILES: O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCN(C(C6CCC(CN7C(C=CC7=O)=O)CC6)=O)CC5)C

Palbociclib-SMCC (Cat. No: I008547) is a Palbociclib derivative with SMCC connector, which can be used to prepare Palbociclib drug conjugates ( antibody-drug conjugates, ADC ), mainly for targeted drug delivery.