Palmatine chloride

• CAT Number: I000305
• CAS Number: 10605-02-4
• Molecular Formula: C21H22NO4.Cl
• Molecular Weight: 387.86
• Purity: ≥95%
• Solubility: DMSO:32mg/mL
• Storage: 3 years -20℃ powder
• IUPAC Name: 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;chloride
• InChI: InChI=1S/C21H22NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,9-12H,7-8H2,1-4H3;1H/q+1;/p-1
• InChIKey: RLQYRXCUPVKSAW-UHFFFAOYSA-M
• SMILES: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC.[Cl-]

Palmatine chloride (Cat.No:I000305) is a natural alkaloid found in various plant sources, including Rhizoma Coptidis. It exhibits a wide range of pharmacological activities, such as antimicrobial, anti-inflammatory, antioxidant, and anticancer effects. Palmatine chloride has been studied for its potential therapeutic applications in various diseases, including cardiovascular disorders, diabetes, and cancer.

Reference

[1]. SHINTARO ISHIKAWA, et al. Influence of Palmatine on Bone Metabolism in Ovariectomized Mice and Cytokine Secretion of Osteoblasts.
[2]. Chen-Wen Xiao, er al. Antifungal activity of berberine hydrochloride and palmatine hydrochloride against Microsporum canis -induced dermatitis in rabbits and underlying mechanism. BMC Complement Altern Med. 2015; 15: 177.